Michael, Mike or Mick McCarthy may refer to:
- Michael McCarthy (Australian footballer) (born 1957), Hawthorn premiership player
- Michael McCarthy (cyclist) (born 1968), American cyclist
- Michael McCarthy (Gaelic footballer), Irish Gaelic footballer from Kerry
- Michael W. McCarthy (born 1971), American thoroughbred racehorse trainer
- Mike McCarthy (baseball) (born 1987), American baseball coach
- Mike McCarthy (gridiron football executive) (born 1953), football executive and scout
- Mick McCarthy (footballer, born 1911) (1911–1973), Irish football goalkeeper
- Mick McCarthy (born 1959), English-born Irish football manager and former player
- Mick McCarthy (Gaelic footballer) (1965–1998), Irish sportsperson
- Mike McCarthy (born 1963), head coach of the National Football League's Green Bay Packers from 2006 to 2018, and from the Dallas Cowboys from 2020 to the present
- Mike McCarthy (rugby union) (born 1981), English-born Irish rugby union player
- Michael McCarthy (journalist) (born c. 1947), British environmentalist, naturalist, journalist and writer
- Mike McCarthy (journalist), British television journalist
- Michael McCarthy (Irish lawyer) (1864–1928), Irish lawyer and anti-clerical author
- Michael McCarthy (bishop), Roman Catholic bishop in Queensland, Australia
- Michael J. McCarthy (general), U.S. Air Force general
- Michael M. McCarthy (1845–1914), Canadian US Army soldier and Medal of Honor recipient
- Michael A. McCarthy, American diplomat