Microcosm or macrocosm, also spelled mikrokosmos or makrokosmos, may refer to:
- Macrocosm (album), seventh studio album by the German electronic composer Peter Frohmader, released in 1990
- Makrokosmos, a series of four volumes of pieces for piano by American composer George Crumb
- "Mic-rocosm", a song by American rapper Prodigy from the album Hegelian Dialectic
- Microcosm (album), 2010 album by Flow
- Microcosmos (Drudkh album)
- Microcosmos (Thy Catafalque album)
- Mikrokosmos (Bartók), a cycle of piano pieces written 1926-1939 by Hungarian composer Béla Bartók
- Mikrokosmos (Turovsky), four cycles of lute pieces, Mikrokosmos I-IV, by Ukrainian-American composer Roman Turovsky
- Mikrokosmos, pseudonym used by former Dark Star frontman Christian Hayes for solo material
- Mikrokosmos, a 1987 performance choreographed by Anne Teresa De Keersmaeker
- "Mikrokosmos", by BTS from the 2019 album Map of the Soul: Persona
- Macrocosm (Star Trek: Voyager), 54th episode of Star Trek: Voyager
- Microcosm (CERN), a museum near Geneva, Switzerland
- Microcosm (clock), a unique clock made by Henry Bridges of Waltham Abbey, England
- Microcosm (hypermedia system), an early hypermedia system that predated the World Wide Web
- Microcosm (video game), a 1993 shoot-'em-up by Psygnosis
- Microcosm Ltd, a UK software protection company
- Microcosmos (film), a 1996 documentary film
- The Microcosm, a 19th-century microscope gallery and shop on Regent Street, London, run by Carpenter and Westley