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Juvenile primary lateral sclerosis
Medical condition / From Wikipedia, the free encyclopedia
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"JPLS" redirects here. For the singular, see JPL.
Juvenile primary lateral sclerosis (JPLS) also known as primary lateral sclerosis, juvenile (PLSJ), is a very rare genetic disorder, with a small number of reported cases, characterized by progressive weakness and stiffness of muscles in the arms, legs, and face. The disorder damages motor neurons, which are specialized nerve cells in the brain and spinal cord that control muscle movement.