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Human polyomavirus 2
Species of virus / From Wikipedia, the free encyclopedia
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"JCV" redirects here. Not to be confused with Jamestown Canyon virus.
Human polyomavirus 2, commonly referred to as the JC virus or John Cunningham virus, is a type of human polyomavirus (formerly known as papovavirus).[3] It was identified by electron microscopy in 1965 by ZuRhein and Chou,[4] and by Silverman and Rubinstein, and later isolated in culture and named using the two initials of a patient, John Cunningham, with progressive multifocal leukoencephalopathy (PML).[5] The virus causes PML and other diseases only in cases of immunodeficiency, as in AIDS or during treatment with immunosuppressive drugs (e.g. in organ transplant patients).[6]
Quick Facts Human polyomavirus 2, Virus classification ...
Human polyomavirus 2 | |
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Immunohistochemical detection of Human polyomavirus 2 protein (stained brown) in a brain biopsy (glia demonstrating progressive multifocal leukoencephalopathy (PML)) | |
Virus classification ![]() | |
(unranked): | Virus |
Realm: | Monodnaviria |
Kingdom: | Shotokuvirae |
Phylum: | Cossaviricota |
Class: | Papovaviricetes |
Order: | Sepolyvirales |
Family: | Polyomaviridae |
Genus: | Betapolyomavirus |
Species: | Human polyomavirus 2 |
Synonyms | |
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