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Familial amyloid polyneuropathy
Medical condition / From Wikipedia, the free encyclopedia
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Familial amyloid polyneuropathy, also called transthyretin-related hereditary amyloidosis, transthyretin amyloidosis abbreviated also as ATTR (hereditary form), or Corino de Andrade's disease,[1] is an autosomal dominant[2] neurodegenerative disease. It is a form of amyloidosis, and was first identified and described by Portuguese neurologist Mário Corino da Costa Andrade, in 1952.[3] FAP is distinct from senile systemic amyloidosis (SSA), which is not inherited, and which was determined to be the primary cause of death for 70% of supercentenarians who have been autopsied.[4] FAP can be ameliorated by liver transplantation.
Familial amyloid polyneuropathy | |
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Other names | FAP |
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Familial amyloid polyneuropathy has an autosomal dominant pattern of inheritance. | |
Specialty | Neurology |