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Adefovir
Chemical compound / From Wikipedia, the free encyclopedia
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Adefovir is a prescription medicine used to treat (chronic) infections with hepatitis B virus. A prodrug form of adefovir was previously called bis-POM PMEA, with trade names Preveon and Hepsera. It is an orally administered nucleotide analog reverse-transcriptase inhibitor (ntRTI). It can be formulated as the pivoxil prodrug adefovir dipivoxil.
Quick Facts Clinical data, Trade names ...
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Clinical data | |
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Trade names | Hepsera |
AHFS/Drugs.com | Monograph |
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Routes of administration | Oral |
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Pharmacokinetic data | |
Bioavailability | 59% |
Protein binding | <4% |
Elimination half-life | 7.5 hours |
Excretion | Urine |
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ECHA InfoCard | 100.106.235 ![]() |
Chemical and physical data | |
Formula | C8H12N5O4P |
Molar mass | 273.189 g·mol−1 |
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