frequently referred to as HER2 (human epidermal growth factor receptor 2) or CD340 (clusterofdifferentiation 340). HER2 is a member of the human epidermal
HOTAIR-mediated overexpression of the HER2 oncogene through sequestration of miR-331-3p, which is a negative regulator ofHER2 expression. In cells, especially
For those whose tumors are HER2-positive, adding the HER2-targeted antibody trastuzumab to chemotherapy reduces the chance of cancer recurrence and death