Nitroglycerin (medication)
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For the undiluted form used as an explosive, see Nitroglycerin.
Nitroglycerin, also known as glyceryl trinitrate (GTN), is a vasodilator used for heart failure, high blood pressure (hypertension), anal fissures, painful periods, and to treat and prevent chest pain caused by decreased blood flow to the heart (angina) or due to the recreational use of cocaine.[1][2][3][4] This includes chest pain from a heart attack.[1] It is taken by mouth, under the tongue, applied to the skin, or by injection into a vein.[1]
Quick Facts Clinical data, Trade names ...
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Trade names | Nitrol, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a601086 |
Routes of administration | Sublingual, transdermal, by mouth, intravenous |
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Bioavailability | <1% |
Metabolism | liver (rapid), red blood cells, vascular wall |
Elimination half-life | 3 minutes |
Excretion | In urine, in bile |
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Formula | C3H5N3O9 |
Molar mass | 227.085 g·mol−1 |
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