Calcitonin gene-related peptide receptor antagonist
Class of drugs / From Wikipedia, the free encyclopedia
Calcitonin gene-related peptide (CGRP) receptor antagonists are a class of drugs that act as antagonists of the calcitonin gene-related peptide receptor (CGRPR).
Several monoclonal antibodies that bind to the CGRP receptor or peptide have been approved for prevention of migraine.[1] Three small molecule CGRPR antagonists are approved in the U.S. as antimigraine agents.[2][3][4] Drugs of this class have also been investigated for use in osteoarthritis.[5]