states. Frankfurt Rhine-Main, Germany's second-largest metropolitan area (after Rhine-Ruhr), is mainly located in Hesse. As a cultural region, Hesse also
seats. Frankfurt is home to influential educational institutions, including the Goethe University with the Universitätsklinikum Frankfurt (de) (Hesse's largest
parts of three German states: Hesse, Rhineland-Palatinate, and Bavaria. The largest cities in the region are Frankfurt am Main, Wiesbaden, Mainz, Darmstadt
Palace near Fulda, Hesse Schlosshotel Kronberg near Frankfurt, Hesse Grandhotel Hessischer Hof in Frankfurt Schloß Wolfsgarten near Frankfurt Panker Estate