Ferredoxin—nitrite reductase
Class of enzymes / From Wikipedia, the free encyclopedia
In enzymology, a ferredoxin—nitrite reductase (EC 1.7.7.1) is an enzyme that catalyzes the chemical reaction
- NH3 + 2 H2O + 6 oxidized ferredoxin
nitrite + 6 reduced ferredoxin + 7 H+
ferredoxin—nitrite reductase | |||||||||
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Identifiers | |||||||||
EC no. | 1.7.7.1 | ||||||||
CAS no. | 37256-44-3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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The 3 substrates of this enzyme are NH3, H2O, and oxidized ferredoxin, whereas its 3 products are nitrite, reduced ferredoxin, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is ammonia:ferredoxin oxidoreductase. This enzyme participates in nitrogen metabolism and nitrogen assimilation. It has 3 cofactors: iron, Siroheme, and Iron-sulfur.
This enzyme can use many different isoforms of ferredoxin. In photosynthesizing tissues, it uses ferredoxin that is reduced by PSI and in the root it uses a form of ferredoxin (FdIII) that has a less negative midpoint potential and can be reduced easily by NADPH.[1]