Feist–Benary synthesis
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Not to be confused with Benary reaction.
The Feist–Benary synthesis is an organic reaction between α-halo ketones and β-dicarbonyl compounds to produce substituted furan compounds.[1] This condensation reaction is catalyzed by amines such as ammonia and pyridine. The first step in the ring synthesis is related to the Knoevenagel condensation. In the second step the enolate displaces an alkyl halogen in a nucleophilic aliphatic substitution.
![Feist Benary synthesis](http://upload.wikimedia.org/wikipedia/commons/f/f3/FeistBenarysynthesis.gif)
Quick Facts Identifiers ...
Feist–Benary synthesis | |
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Named after | Franz Feist Erich Benary |
Reaction type | Ring forming reaction |
Identifiers | |
RSC ontology ID | RXNO:0000501 |
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