Oocyte activation
Processes in fertilization / From Wikipedia, the free encyclopedia
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Oocyte (or ovum/egg) activation is a series of processes that occur in the oocyte during fertilization.
Sperm entry causes calcium release into the oocyte. In mammals, this is caused by the introduction of phospholipase C isoform zeta (PLCĪ¶) from the sperm cytoplasm.[1] Activation of the ovum includes the following events:
- Cortical reaction to block against other sperm cells
- Activation of egg metabolism
- Reactivation of meiosis
- DNA synthesis