Dieulafoy's lesion
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Dieulafoy's lesion (French: [djølafwa]) is a medical condition characterized by a large tortuous artery[2] most commonly in the stomach wall (submucosal) that erodes and bleeds. It can present in any part of the gastrointestinal tract.[3] It can cause gastric hemorrhage[4] but is relatively uncommon. It is thought to cause less than 5% of all gastrointestinal bleeds in adults. It was named after French surgeon Paul Georges Dieulafoy, who described this condition in his paper "Exulceratio simplex: Leçons 1-3" in 1898.[5][6] It is also called "caliber-persistent artery" or "aneurysm" of gastric vessels. However, unlike most other aneurysms, these are thought to be developmental malformations rather than degenerative changes.
Dieulafoy's lesion | |
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Other names | Exulceratio simplex Dieulafoy |
Blood supply of stomach | |
Pronunciation |
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Specialty | Gastroenterology |
Symptoms | Hematemesis, melena, hematochezia, anemia |
Usual onset | 52 years (average age) |
Causes | Aberrant submucosal arteriole |
Diagnostic method | Upper endoscopy |
Treatment | Endoscopic therapy with endoclip, argon plasma coagulation, electrocautery, epinephrine injection, etc |
Prognosis | 8% mortality[1] |
Frequency | 1.5% of gastrointestinal bleeding |