David Watson may refer to:
- Dave Watson (born 1961), English footballer of the 1980s and 1990s, played for Everton F.C.
- Dave Watson (American football) (1941–2021), professional American football player
- Dave Watson (cyclist) (born 1946), Australian Olympic cyclist
- Dave Watson (ice hockey) (born 1958), retired Canadian professional ice hockey forward
- Dave Watson (racing driver) (born 1945), American racing driver
- Dave Watson (rugby league) (born 1966), New Zealand international of the 1980s and 1990s
- David Watson (1920s rugby league) (1900–1982), Australian rugby player
- David Watson (coach) (born 1976), American football coach
- David Watson (cricketer) (1919–1943), English cricketer
- David Watson (footballer, born 1946), English footballer of the 1970s and 1980s, played for Sunderland
- David Watson (footballer, born 1973), English football goalkeeper of the 1990s, played for Barnsley
- David Watson (footballer, born 2005), Scottish footballer with Kilmarnock
- David Watson (rugby union) (1854–1906), Scotland international rugby union player
- David Watson (actor) (1940–2014), American actor of film, television and theatre
- David Watson (artist) (born 1944), English industrial painter
- David Watson (British musician), record producer, singer and musician
- David Watson (dancer) (born 1968), professional dancer
- David Watson (New Zealand musician) (born 1960), musician and composer from New Zealand
- David R. Watson, alias "Iolo", American bowyer and musician
- Dave Watson (playwright) (c. 1946–1998), actor and playwright
- David Watson (academic) (1949–2015), principal of Green Templeton College, Oxford, UK
- David Watson (anarchist) (born 1951), American anarchist author
- David Watson (British Army officer) (1704–1761), Scottish officer and military engineer
- David Watson (evangelist) (1933–1984), English evangelist and author
- Sir David Watson (general) (1869–1922), Canadian World War I general
- David Watson (psychologist), American psychologist
- David C. C. Watson (1920–2004), English creationist and author
- David Joseph Watson (died 1948), American murderer, executed in Florida
- David M. Watson (born 1973), Australian ornithologist and ecologist
- D. M. S. Watson (1886–1973), British palaeontologist
- David McCloy Watson (1902-1980), Irish accountant
- David Mowat Watson (1891–1972), British civil engineer
- David Paul Watson (fl. 1990), botanist, horticulturist and cannabis breeder, founder of Hortapharm B.V.