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Class of enzymes From Wikipedia, the free encyclopedia
In enzymology, a D-alanine—alanyl-poly(glycerolphosphate) ligase (EC 6.3.2.16) is an enzyme that catalyzes the chemical reaction
D-Alanine—alanyl-poly(glycerolphosphate) ligase | |||||||||
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Identifiers | |||||||||
EC no. | 6.3.2.16 | ||||||||
CAS no. | 9046-58-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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The 3 substrates of this enzyme are ATP, D-alanine, and alanyl-poly(glycerolphosphate), whereas its 3 products are ADP, phosphate, and D-alanyl-alanyl-poly(glycerolphosphate).
This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-amino-acid ligases (peptide synthases). The systematic name of this enzyme class is D-alanine:alanyl-poly(glycerolphosphate) ligase (ADP-forming). Other names in common use include D-alanyl-alanyl-poly(glycerolphosphate) synthetase, D-alanine:membrane-acceptor ligase, D-alanylalanylpoly(phosphoglycerol) synthetase, D-alanyl-poly(phosphoglycerol) synthetase, and D-alanine-membrane acceptor-ligase. This enzyme participates in d-alanine metabolism.
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