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Efavirenz/emtricitabine/tenofovir
Combination drug for HIV / From Wikipedia, the free encyclopedia
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Efavirenz/emtricitabine/tenofovir, sold under the brand name Atripla among others, is a fixed-dose combination antiretroviral medication used to treat HIV/AIDS.[7][6] It contains efavirenz, emtricitabine, and tenofovir disoproxil.[7][6] It can be used by itself or together with other antiretroviral medications.[7] It is taken by mouth.[5][6][7]
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Combination of | |
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Efavirenz | non-nucleoside reverse transcriptase inhibitor |
Emtricitabine | nucleoside analog reverse transcriptase inhibitor |
Tenofovir disoproxil | nucleotide analog reverse transcriptase inhibitor |
Clinical data | |
Trade names | Atripla, Viraday, others |
Other names | tenofovir disoproxil fumarate/emtricitabine/efavirenz |
AHFS/Drugs.com | Professional Drug Facts |
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Routes of administration | By mouth |
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Common side effects include headache, trouble sleeping, sleepiness, and unsteadiness.[5] Serious side effects may include high blood lactate levels, psychiatric symptoms, and enlargement of the liver.[5] It should not be used in children.[7] If used during the first trimester of pregnancy harm to the baby may occur.[5]
Efavirenz/emtricitabine/tenofovir was approved for medical use in the United States in 2006,[5][8] and in the European Union in 2007.[6] It is on the World Health Organization's List of Essential Medicines.[9] Efavirenz/emtricitabine/tenofovir is available as a generic medication.[10][11]