Aminophenazone
Non-narcotic analgesic drug / From Wikipedia, the free encyclopedia
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Aminophenazone (or aminopyrine, amidopyrine, Pyramidon) is a non-narcotic analgesic substance. It is a pyrazolone and a derivative of phenazone, which also has anti-inflammatory and antipyretic properties. While inexpensive and effective, especially in the treatment of rheumatism, the drug carries a serious risk of severe and sometimes fatal side-effects, including agranulocytosis.[citation needed] While its production and use have been banned in many countries, including France, Thailand, India and Japan, it is still sometimes used in the developing world.[citation needed]
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Metabolism | N-demethylation[1] |
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ECHA InfoCard | 100.000.332 |
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Formula | C13H17N3O |
Molar mass | 231.299 g·mol−1 |
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A breath test with 13C-labeled aminopyrine has been used as a non-invasive measure of cytochrome P-450 metabolic activity in liver-function tests.[1] It is also used in measuring the total body water in the human body system.[2]