Arachidonate 5-lipoxygenase
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Arachidonate 5-lipoxygenase, also known as ALOX5, 5-lipoxygenase, 5-LOX, or 5-LO, is a non-heme iron-containing enzyme (EC 1.13.11.34) that in humans is encoded by the ALOX5 gene.[1] Arachidonate 5-lipoxygenase is a member of the lipoxygenase family of enzymes. It transforms essential fatty acids (EFA) substrates into leukotrienes as well as a wide range of other biologically active products. ALOX5 is a current target for pharmaceutical intervention in a number of diseases.
Quick Facts Identifiers, Aliases ...
arachidonate 5-lipoxygenase | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | 5-lipoxygenase | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | GeneCards: ; OMA:- orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Quick Facts Identifiers, EC no. ...
arachidonate 5-lipoxygenase | |||||||||
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Identifiers | |||||||||
EC no. | 1.13.11.34 | ||||||||
CAS no. | 80619-02-9[permanent dead link] | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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