Loading AI tools
Chemical compound From Wikipedia, the free encyclopedia
4,4'-Dimethylaminorex (abbreviated as 4,4'-DMAR), sometimes referred to by the street name "Serotoni", is a psychostimulant and entactogen designer drug related to aminorex, 4-methylaminorex, and pemoline.[3] It was first detected in the Netherlands in December 2012,[4] and has been sold as a designer drug around Europe since mid-2013.
Clinical data | |
---|---|
Other names | 4,4'-DMAR |
ATC code |
|
Legal status | |
Legal status | |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C11H14N2O |
Molar mass | 190.246 g·mol−1 |
3D model (JSmol) | |
| |
|
4,4'-DMAR had been linked to at least 31 deaths in Hungary, Poland, and the UK by February 2014, mostly when consumed in combination with other drugs.[5] Nineteen deaths linked to 4,4'-DMAR were reported in Northern Ireland in the same time period.[6]
4,4'-DMAR acts as a potent and balanced serotonin-norepinephrine-dopamine releasing agent (SNDRA), with EC50 values for serotonin, norepinephrine, and dopamine release of 18.5 nM, 26.9 nM, and 8.6 nM, respectively.[3]
The UK Home Office expressed intent to ban 4,4'-DMAR following advice from the Advisory Council on the Misuse of Drugs[7] and subsequently it became a class A drug on 11 March 2015.[8]
4,4'-DMAR is an Anlage II controlled substance in Germany as of May 2015[update].[9]
Sweden's public health agency suggested to classify 4,4'-DMAR as hazardous substance on November 10, 2014.[10]
4,4'-DMAR is also banned in the Czech Republic.[11]
4,4'-DMAR is a Schedule I controlled substance in the US as of November 8, 2021. It only received two public comments during its public commenting period prior to being scheduled.[12][13]
Seamless Wikipedia browsing. On steroids.
Every time you click a link to Wikipedia, Wiktionary or Wikiquote in your browser's search results, it will show the modern Wikiwand interface.
Wikiwand extension is a five stars, simple, with minimum permission required to keep your browsing private, safe and transparent.