Sindetin

Sindetin je protein koji je kod ljudi kodiran genom VPS50. Komponenta je EARP kompleksa koji je uključen u endocitnu reciklažu.^[5]

Sindetin
Identifikatori
Aliasi	VPS50
Vanjski ID-jevi	OMIM: 616465 MGI: 1920538 HomoloGene: 11498 GeneCards: VPS50
Lokacija gena (čovjek) Hrom. Hromosom 7 (čovjek)[1] Bend 7q21.2-q21.3 Početak 93,232,340 bp[1] Kraj 93,361,123 bp[1]
Lokacija gena (miš) Hrom. Hromosom 6 (miš)[2] Bend 6|6 A1 Početak 3,498,382 bp[2] Kraj 3,603,531 bp[2]
Ontologija gena Molekularna funkcija • SNARE binding • GO:0001948, GO:0016582 vezivanje za proteine Ćelijska komponenta • reciklirajući endosom • EARP complex • endozom • Egzosom • membrana • citosol Biološki proces • protein transport • retrograde transport, endosome to Golgi • endocytic recycling • GO:0015915 transport Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	55610	73288
Ensembl	ENSG00000004766	ENSMUSG00000001376
UniProt	Q96JG6	Q8CI71
RefSeq (mRNK)	NM_001257998 NM_017667 NM_024553	NM_001167750 NM_001167751 NM_024260
RefSeq (bjelančevina)	NP_001244927 NP_060137 NP_078829	NP_001161222 NP_001161223 NP_077222
Lokacija (UCSC)	Chr 7: 93.23 – 93.36 Mb	Chr 6: 3.5 – 3.6 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Reference

1. GRCh38: Ensembl release 89: ENSG00000004766 - Ensembl, maj 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000001376 - Ensembl, maj 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Schindler C, Chen Y, Pu J, Guo X, Bonifacino JS (2015). "EARP is a multisubunit tethering complex involved in endocytic recycling". Nature Cell Biology. 17 (5): 639–50. doi:10.1038/ncb3129. PMC 4417048. PMID 25799061.