Trichrome staining
Histological staining method / From Wikipedia, the free encyclopedia
"Trichrome" redirects here. For three color vision, see Trichromacy. For the band and album, see Trichromes. For three-color systems, see CMY color model, RGB color model, and RYB color model. Not to be confused with Trichome.
Trichrome staining is a histological staining method that uses two or more acid dyes in conjunction with a polyacid. Staining differentiates tissues by tinting them in contrasting colours. It increases the contrast of microscopic features in cells and tissues, which makes them easier to see when viewed through a microscope.
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The word trichrome means "three colours". The first staining protocol that was described as "trichrome" was Mallory's trichrome stain, which differentially stained erythrocytes to a red colour, muscle tissue to a red colour, and collagen to a blue colour. Some other trichrome staining protocols are the Masson's trichrome stain, Lillie's trichrome, and the Gömöri trichrome stain.