Sialidase-2 is an enzyme that in humans is encoded by the NEU2 gene.[5][6][7]
Quick Facts NEU2, Available structures ...
NEU2 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/d/d9/Protein_NEU2_PDB_1snt.png/250px-Protein_NEU2_PDB_1snt.png) |
Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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1SNT, 1SO7, 1VCU, 2F0Z, 2F10, 2F11, 2F12, 2F13, 2F24, 2F25, 2F26, 2F27, 2F28, 2F29, 4NC5, 4NCS |
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Identifiers |
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Aliases | NEU2, SIAL2, neuraminidase 2 (cytosolic sialidase), neuraminidase 2 |
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External IDs | OMIM: 605528; MGI: 1344417; HomoloGene: 3927; GeneCards: NEU2; OMA:NEU2 - orthologs |
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Wikidata |
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This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Expression studies in COS-7 cells confirmed that this gene encodes a functional sialidase. Its cytosolic localization was demonstrated by cell fractionation experiments.[7]