![cover image](https://wikiwandv2-19431.kxcdn.com/_next/image?url=https://upload.wikimedia.org/wikipedia/commons/thumb/8/82/JC-Virus.jpg/640px-JC-Virus.jpg&w=640&q=50)
Human polyomavirus 2
Species of virus / From Wikipedia, the free encyclopedia
"JCV" redirects here. Not to be confused with Jamestown Canyon virus.
Human polyomavirus 2, commonly referred to as the JC virus or John Cunningham virus, is a type of human polyomavirus (formerly known as papovavirus).[3] It was identified by electron microscopy in 1965 by ZuRhein and Chou,[4] and by Silverman and Rubinstein, and later isolated in culture and named using the two initials of a patient, John Cunningham, with progressive multifocal leukoencephalopathy (PML).[5] The virus causes PML and other diseases only in cases of immunodeficiency, as in AIDS or during treatment with immunosuppressive drugs (e.g. in organ transplant patients).[6]
Quick Facts Human polyomavirus 2, Virus classification ...
Human polyomavirus 2 | |
---|---|
![]() | |
Immunohistochemical detection of Human polyomavirus 2 protein (stained brown) in a brain biopsy (glia demonstrating progressive multifocal leukoencephalopathy (PML)) | |
Virus classification ![]() | |
(unranked): | Virus |
Realm: | Monodnaviria |
Kingdom: | Shotokuvirae |
Phylum: | Cossaviricota |
Class: | Papovaviricetes |
Order: | Sepolyvirales |
Family: | Polyomaviridae |
Genus: | Betapolyomavirus |
Species: | Human polyomavirus 2 |
Synonyms | |
Close