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Dimenhydrinate
Anti-emetic and antihistamine medication / From Wikipedia, the free encyclopedia
Not to be confused with diphenhydramine.
"Dramamine" redirects here. For other uses, see Dramamine (disambiguation).
Dimenhydrinate, sold under the brand name Dramamine, among others, is an over-the-counter medication used to treat motion sickness and nausea. Dimenhydrinate is a theoclate salt composed of diphenhydramine (an ethanolamine derivative) and 8-chlorotheophylline (a chlorinated theophylline derivative) in a 1:1 ratio.[2]
Quick Facts Combination of, Diphenhydramine ...
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Diphenhydramine | Antihistamine, sedative |
8-chlorotheophylline | Stimulant |
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Trade names | Dramamine, Draminate, Gravol, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a607046 |
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Routes of administration | By mouth, rectal, intravascular, intramuscular |
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Metabolism | Liver |
Elimination half-life | 5.5 hours[1] (diphenhydramine component) |
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ECHA InfoCard | 100.007.593 ![]() |
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Dimenhydrinate was introduced to the market by G.D. Searle in 1949.[3][4]