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Cyclopyrrolones
Class of chemical compounds / From Wikipedia, the free encyclopedia
Cyclopyrrolones are a family of hypnotic and anxiolytic nonbenzodiazepine drugs with similar pharmacological profiles to the benzodiazepine derivatives.
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Although cyclopyrrolones are chemically unrelated to benzodiazepines, they function via the benzodiazepine receptor of neurotransmitter GABA.[1] The best-known cyclopyrrolone derivatives are zopiclone (Imovane) and its active single-enantiomer component, eszopiclone (Lunesta), which are used to treat insomnia, and have a known potential for abuse. Other cyclopyrrolones include:
- Pagoclone – anxiolytic
- Pazinaclone – anxiolytic
- Suproclone – anxiolytic
- Suriclone – anxiolytic