Template:PBB/3757维基媒体模板 / 維基百科,自由的 encyclopedia 事实速览 Potassium voltage-gated channel, subfamily H (eag-related), member 2, 有效结构 ...Potassium voltage-gated channel, subfamily H (eag-related), member 2 PDB rendering of the N-terminal domain based on 1byw. This domain is just a very small piece of the total channel. 有效结构 PDB 直系同源检索:PDBe, RCSB PDB查询代码列表 1BYW, 1UJL, 2L0W, 2L1M, 2L4R, 2LE7, 4HP9, 4HQA 标识代号 KCNH2; ERG1; HERG; HERG1; Kv11.1; LQT2; SQT1扩展标识 遗传学:152427 鼠基因:1341722 同源基因:201 IUPHAR: Kv11.1 ChEMBL: 240 GeneCards: KCNH2 Gene 基因本体论描述 分子功能 · phosphorelay sensor kinase activity · inward rectifier potassium channel activity · voltage-gated potassium channel activity · delayed rectifier potassium channel activity · protein binding · ubiquitin protein ligase binding · identical protein binding · protein homodimerization activity · voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 细胞成分 · nuclear envelope · cytoplasm · plasma membrane · voltage-gated potassium channel complex · cell surface 生物过程 · phosphorelay signal transduction system · regulation of heart rate by hormone · synaptic transmission · signal transduction by phosphorylation · cellular response to drug · regulation of membrane potential · potassium ion homeostasis · cardiac muscle contraction · regulation of membrane repolarization · regulation of ventricular cardiac muscle cell membrane repolarization · potassium ion export · potassium ion transmembrane transport · ventricular cardiac muscle cell action potential · membrane depolarization during action potential · membrane repolarization during action potential · membrane repolarization during cardiac muscle cell action potential · regulation of heart rate by cardiac conduction · regulation of potassium ion transmembrane transport · negative regulation of potassium ion transmembrane transport · positive regulation of potassium ion transmembrane transport · negative regulation of potassium ion export Sources: Amigo / QuickGO RNA表达模式 更多表达数据直系同源体物种 人类 小鼠Entrez 3757 16511Ensembl ENSG00000055118 ENSMUSG00000038319UniProt Q12809 O35219mRNA序列 NM_000238 NM_001294162蛋白序列 NP_000229 NP_001281091基因位置 Chr 7:150.64 – 150.68 Mb Chr 5:24.32 – 24.35 MbPubMed查询 [1] [2]查论编关闭
事实速览 Potassium voltage-gated channel, subfamily H (eag-related), member 2, 有效结构 ...Potassium voltage-gated channel, subfamily H (eag-related), member 2 PDB rendering of the N-terminal domain based on 1byw. This domain is just a very small piece of the total channel. 有效结构 PDB 直系同源检索:PDBe, RCSB PDB查询代码列表 1BYW, 1UJL, 2L0W, 2L1M, 2L4R, 2LE7, 4HP9, 4HQA 标识代号 KCNH2; ERG1; HERG; HERG1; Kv11.1; LQT2; SQT1扩展标识 遗传学:152427 鼠基因:1341722 同源基因:201 IUPHAR: Kv11.1 ChEMBL: 240 GeneCards: KCNH2 Gene 基因本体论描述 分子功能 · phosphorelay sensor kinase activity · inward rectifier potassium channel activity · voltage-gated potassium channel activity · delayed rectifier potassium channel activity · protein binding · ubiquitin protein ligase binding · identical protein binding · protein homodimerization activity · voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 细胞成分 · nuclear envelope · cytoplasm · plasma membrane · voltage-gated potassium channel complex · cell surface 生物过程 · phosphorelay signal transduction system · regulation of heart rate by hormone · synaptic transmission · signal transduction by phosphorylation · cellular response to drug · regulation of membrane potential · potassium ion homeostasis · cardiac muscle contraction · regulation of membrane repolarization · regulation of ventricular cardiac muscle cell membrane repolarization · potassium ion export · potassium ion transmembrane transport · ventricular cardiac muscle cell action potential · membrane depolarization during action potential · membrane repolarization during action potential · membrane repolarization during cardiac muscle cell action potential · regulation of heart rate by cardiac conduction · regulation of potassium ion transmembrane transport · negative regulation of potassium ion transmembrane transport · positive regulation of potassium ion transmembrane transport · negative regulation of potassium ion export Sources: Amigo / QuickGO RNA表达模式 更多表达数据直系同源体物种 人类 小鼠Entrez 3757 16511Ensembl ENSG00000055118 ENSMUSG00000038319UniProt Q12809 O35219mRNA序列 NM_000238 NM_001294162蛋白序列 NP_000229 NP_001281091基因位置 Chr 7:150.64 – 150.68 Mb Chr 5:24.32 – 24.35 MbPubMed查询 [1] [2]查论编关闭