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From Wikipedia, the free encyclopedia
Aldosterone synthase (or 18-hydroxylase) is a steroid hydroxylase cytochrome P450 enzyme involved in the biosynthesis of the mineralocorticoid aldosterone. Officially named cytochrome P450, family 11, subfamily B, polypeptide 2, it is a protein which is only expressed in the zona glomerulosa[1] of the adrenal cortex and is primarily regulated by the renin-angiotensin system.[2]