File:Basal_ganglia_in_treatment_of_Parkinson's.svg
From Wikipedia, the free encyclopedia
Size of this PNG preview of this SVG file: 417 × 600 pixels. Other resolutions: 167 × 240 pixels | 334 × 480 pixels | 534 × 768 pixels | 712 × 1,024 pixels | 1,423 × 2,048 pixels | 1,010 × 1,453 pixels.
Original file (SVG file, nominally 1,010 × 1,453 pixels, file size: 345 KB)
This is a file from the Wikimedia Commons. Information from its description page there is shown below. Commons is a freely licensed media file repository. You can help. |
Summary
DescriptionBasal ganglia in treatment of Parkinson's.svg |
English: Circuits of the basal ganglia in treatment of Parkinson's disease. Levodopa, dopamine agonists and MAO-B inhibitors stimulate excitatory signals from the thalamus to the cortex by effects on the striatum, compensating for decreased dopaminergic signals from substantia nigra (seen at bottom right). Picture shows 2 coronal slices that have been superimposed to include the involved basal ganglia structures. + and - signs at the point of the arrows indicate respectively whether the pathway is excitatory or inhibitory in effect. Green arrows refer to excitatory glutamatergic pathways, red arrows refer to inhibitory GABAergic pathways and turquoise arrows refer to dopaminergic pathways that are excitatory on the direct pathway and inhibitory on the indirect pathway. Dis-inhibitory pathways are in effect excitatory on the feedback to the cortex, while dis-dis-inhibitory pathways are inhibitory. |
Date | |
Source | Derivative of File:Basal ganglia circuits.png |
Author | Mikael Häggström, based on image by Andrew Gillies/User:Anaru |
Other versions |
Derivative works of this file: Basal ganglia in treatment of Parkinson's-IT.svg |
Basal ganglia gallery
-
Basal ganglia without Parkinson's disease.png.
(Derived from Basal ganglia circuits.svg with small change)
Licensing
I, the copyright holder of this work, hereby publish it under the following license:
This file is licensed under the Creative Commons Attribution-Share Alike 3.0 Unported license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.
Items portrayed in this file
depicts
5 June 2010
image/svg+xml
b4135a25608bc00718765584fca69f1f54b15272
352,997 byte
1,453 pixel
1,010 pixel
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 07:35, 25 August 2010 | 1,010 × 1,453 (345 KB) | Mikael Häggström | Removed pars reticularis pathways for simplification, as they appear to be of relatively minor importance in Parkinson's disease. Reinserted brain at top. | |
16:43, 5 June 2010 | 1,010 × 1,453 (352 KB) | Mikael Häggström | {{Information |Description={{en|1=f}} |Source={{own}} |Author=Mikael Häggström |Date=f |Permission= |other_versions= }} |
File usage
The following pages on the English Wikipedia use this file (pages on other projects are not listed):
Global file usage
The following other wikis use this file: